Flight José Marti International Airport departs from Havana José Marti International Airport at 13:50 and arrives at Panama City Tocumen International Airport at 16:37.
The flighttime is about 3h 47m. The distance travelled ("as the bird flies"): 414 Km. So the average speed is roughly 109 Km.
There is an 1 hour time difference between Havana and Panama City